Yazar "Gunel-Ozcan, Aysen" için listeleme
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The frequency of Familial Mediterranean fever gene mutations and genotypes at Kirikkale and comparison with the mean of regional MEFV mutation frequency of Turkey
Kocakap, Derya Beyza Sayin; Gunel-Ozcan, Aysen; Cabuk, Feryal; Ensari, Cuneyt (Springer, 2014)In this study we have retrospectively analysed the mutation spectrum of the 351 Familial Mediterranean fever patients referred to KA +/- rA +/- kkale University Faculty of Medicine, Department of Medical Genetics Laboratory ... -
Hereditary haemochromatosis gene (HFE) H63D mutation shows an association with abnormal sperm motility
Gunel-Ozcan, Aysen; Basar, M. Murad; Kisa, Ucler; Ankarali, Handan C. (Springer, 2009)The aim of this study was to screen infertile men for HFE H63D mutation in correlation with clinical characteristics of infertile men (sperm concentration, sperm motility, morphology, testicular volume, Follicle Stimulating ... -
Molecular and functional analysis of a novel recombinant clone of rat (Rattus norvegicus) CD40 ligand (CD40L) gene
Esendagli, Gunes; Gunel-Ozcan, Aysen; Canpinar, Hande; Guc, Dicle (Springer, 2009)Genetic material obtained from various individuals may contain certain polymorphisms which may conflict with the predetermined DNA sequence and consequently, may modulate the function of gene products. In this study, coding ... -
Primary tumor cells obtained from MNU-induced mammary carcinomas show immune heterogeneity which can be modulated by low-efficiency transfection of CD40L gene
Esendagli, Gunes; Canpinar, Hande; Yilmaz, Guldal; Gunel-Ozcan, Aysen; Guc, M. Oguz; Kansu, Emin; Guc, Dicle (Taylor & Francis Inc, 2009)The presence of CD40 on carcinoma cells is an important factor for the generation of tumor-specific responses induced by CD40 ligation. In an N-methyl-N-nitrosourea (MNU)-induced autochthonous mammary tumor model, we ... -
The spectrum of FMF mutations and genotypes in the referrals to molecular genetic laboratory at KÄaut +/- rÄaut +/- kkale University in Turkey
Gunel-Ozcan, Aysen; Sayin, Derya Beyza; Misirlioglu, Emine Dibek; Guliter, Sefa; Yakaryilmaz, Fahri; Ensari, Cuneyt (Springer, 2009)Familial Mediterranean Fever (FMF) is an autosomal recessive genetic disorder characterised by recurrent and self-limited abdominal pain, synovitis and pleuritis. MEFV gene mutations are responsible from the disease and ...